|
Category:flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | yellow clear liquid (est) |
| Assay: | 96.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.92600 to 0.93600 @ 25.00 °C.
|
| Pounds per Gallon - (est).: | 7.705 to 7.788
|
| Refractive Index: | 1.40600 to 1.41600 @ 20.00 °C.
|
| Melting Point: | -30.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 128.00 °C. @ 760.00 mm Hg
|
| Vapor Pressure: | 10.000000 mmHg @ 20.00 °C. |
| Vapor Density: | 3.9 ( Air = 1 ) |
| Flash Point: | 83.00 °F. TCC ( 28.33 °C. )
|
| logP (o/w): | -0.321 (est) |
| Soluble in: |
| | alcohol | | | water, slightly | | | water, 2.113e+005 mg/L @ 25 °C (est) |
| Similar Items:note |
| acetyl isobutyryl |
| hexane-3,4-dione |
Organoleptic Properties:
| Odor Type: buttery |
Odor Strength:high , recommend smelling in a 1.00 % solution or less |
| Substantivity:220 hour(s) at 100.00 % |
| dry sweet caramellic buttery oily fatty creamy phenolic fruity |
Odor Description:at 1.00 % in dipropylene glycol. dry sweet caramel butter oily fatty creamy phenolic fruity Luebke, William tgsc, (1988) |
| Odor sample from: Fritzsche Dodge & Olcott, Inc. |
| sweet creamy caramellic buttery fruity jammy |
Odor Description:Sweet, creamy, caramellic, buttery with a fruity jammy nuance Mosciano, Gerard P&F 16, No. 6, 43, (1991) |
| Flavor Type: creamy |
| creamy fruity toasted brown caramellic |
Taste Description: at 50.00 ppm. Creamy, fruity, toasted brown caramellic notes Mosciano, Gerard P&F 16, No. 6, 43, (1991) |
| Odor and/or flavor descriptions from others (if found). |
| Sigma-Aldrich |
| 2,3-Hexanedione, ≥95%, FG |
| Odor Description:butter; creamy; oily; sweet |
| Taste Description:creamy fruity toasted brown caramel |
| Indukern F&F |
| ACETYL BUTYRYL |
| Odor Description:SWEET, CREAMY, BUTTER |
Cosmetic Information:
Suppliers:
| Ambles Nature et Chimie |
| 3.4-HEXANEDIONE
|
| Anhui Haibei |
| Acetyl Butyryl
Odor: Dry sweet butter oily creamy fatty fruity jam |
| Augustus Oils |
| 2,3 Hexanedione
|
| Services |
| Beijing Lys Chemicals |
| 2,3-Hexanedione
|
| BOC Sciences |
| For experimental / research use only. |
| 2,3-Hexanedione
|
| CJ Latta & Associates |
| ACETYL BUTYRYL
|
| Diffusions Aromatiques |
| 2,3 HEXANEDIONE
|
| EMD Millipore |
| For experimental / research use only. |
| 2,3-Hexanedione
|
| Ernesto Ventós |
| 2,3-HEXANEDIONE
Odor: CREAMY, SWEET, BUTTERY, CHEESY |
| Frutarom |
| 2,3-HEXANEDIONE
KOSHER Flavor: Buttery, Fatty, Sweet, Oily, Creamy |
| CBD Offering |
| IFF |
| 2,3-HEXANEDIONE
KOSHER Flavor: Buttery, Fatty, Sweet, Oily, Creamy |
| Indukern F&F |
| ACETYL BUTYRYL
Odor: SWEET, CREAMY, BUTTER |
| Inoue Perfumery |
| ACETYL BUTYRYL
|
| Lluch Essence |
| ACETYL BUTIRYL NATURAL
|
| Lluch Essence |
| ACETYL BUTIRYL
Odor: CREAMY, SWEET, BUTTERY |
| M&U International |
| 2,3-HEXANDIONE
|
| Nagar Haveli Perfumes & Aromatics |
| Acetyl Butyryl
Odor: Sweet, creamy, caramellic, buttery with a fruity jammy nuance |
| Nagar Haveli Perfumes & Aromatics |
| Acetyl Butyryl
Natural Odor: Sweet, creamy, caramellic, buttery with a fruity jammy nuance |
| Pearlchem Corporation |
| Acetyl Butyryl
|
| Santa Cruz Biotechnology |
| For experimental / research use only. |
| 2,3-Hexanedione ≥90%
|
| Sigma-Aldrich |
| 2,3-Hexanedione, ≥95%, FG
Odor: butter; creamy; oily; sweet |
| Certified Food Grade Products |
| Sigma-Aldrich |
| 2,3-Hexanedione, natural, 96%, FG
|
| SRS Aromatics |
| 2,3-HEXANEDIONE (FG)
|
| Synerzine |
| Acetyl Butyryl (natural)
|
| Synerzine |
| Acetyl Butyryl (synthetic)
|
| Tianjin Danjun International |
| 2,3-Hexanedione
|
| United International |
| 2,3-Hexanedione
|
| Vigon International |
| Acetyl Butyryl (2,3-Hexanedione)
Odor: Dry sweet butter oily creamy fatty fruity jam |
| WholeChem |
| Acetyl Butyryl, Natural
|
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xi - Irritant |
R 10 - Flammable. R 36/37/38 - Irritating to eyes, respiratory system, and skin. S 02 - Keep out of the reach of children. S 16 - Keep away from sources of ignition - No Smoking. S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
|
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
Flammable liquids (Category 3), H226 Skin irritation (Category 2), H315 Eye irritation (Category 2A), H319 Specific target organ toxicity - single exposure (Category 3), Respiratory system, H335
|
| GHS Label elements, including precautionary statements |
| |
| Pictogram |   |
| |
| Signal word | Warning |
| Hazard statement(s) |
H226 - Flammable liquid and vapour H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation
|
| Precautionary statement(s) |
P210 - Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233 - Keep container tightly closed. P240 - Ground/bond container and receiving equipment. P241 - Use explosion-proof electrical/ventilating/lighting/…/equipment. P242 - Use only non-sparking tools. P243 - Take precautionary measures against static discharge. P261 - Avoid breathing dust/fume/gas/mist/vapours/spray. P264 - Wash skin thouroughly after handling. P271 - Use only outdoors or in a well-ventilated area. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P303 + P361 + P353 - IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P304 + P340 - IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312 - Call a POISON CENTER or doctor/physician if you feel unwell. P332 + P313 - IF SKIN irritation occurs: Get medical advice/attention. P337 + P313 - IF eye irritation persists: Get medical advice/attention. P362 - Take off contaminated clothing and wash before reuse. P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam for extinction. P403 + P233 - Store in a well-ventilated place. Keep container tightly closed. P403 + P235 - Store in a well-ventilated place. Keep cool. P405 - Store locked up. P501 - Dispose of contents/ container to an approved waste disposal plant.
|
| Human Experience: |
| 4 % solution: no irritation or sensitization. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 > 5000 mg/kg (Moreno, 1977d)
oral-rat LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 697, 1979.
|
| Dermal Toxicity: |
skin-rabbit LD50 > 5000 mg/kg Food and Cosmetics Toxicology. Vol. 17, Pg. 697, 1979.
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | flavor and fragrance agents |
| RIFM Fragrance Material Safety Assessment: Search |
| IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice |
| Recommendation for acetyl butyryl usage levels up to: | | | 1.0000 % in the fragrance concentrate.
|
| |
| Maximised Survey-derived Daily Intakes (MSDI-EU): | 8.50 (μg/capita/day) |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 3 |
| Click here to view publication 3 |
| | average usual ppm | average maximum ppm |
| baked goods: | - | 6.60000 |
| beverages(nonalcoholic): | - | 6.60000 |
| beverages(alcoholic): | - | - |
| breakfast cereal: | - | - |
| cheese: | - | - |
| chewing gum: | - | - |
| condiments / relishes: | - | - |
| confectionery froastings: | - | - |
| egg products: | - | - |
| fats / oils: | - | - |
| fish products: | - | - |
| frozen dairy: | - | 4.80000 |
| fruit ices: | - | 4.80000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | - | - |
| hard candy: | - | 7.30000 |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | - | - |
| milk products: | - | - |
| nut products: | - | - |
| other grains: | - | - |
| poultry: | - | - |
| processed fruits: | - | - |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | - | - |
| snack foods: | - | - |
| soft candy: | - | - |
| soups: | - | - |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
Safety References:
European Food Safety Athority(EFSA):Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
|
European Food Safety Authority (EFSA) reference(s):
|
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Flavouring Group Evaluation 11 (FGE.11): Aliphatic dialcohols, diketones, and hydroxyketones from chemical group 10 (Commission Regulation (EC) No 1565/2000 of 18 July 2000) View page or View pdf
|
Flavouring Group Evaluation 11, Revision 1 (FGE.11Rev1) - Aliphatic dialcohols, diketones, and hydroxyketones from chemical group 10 - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Materials in contact with Food (AFC) View page or View pdf
|
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):3848-24-6 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :19707 |
| National Institute of Allergy and Infectious Diseases:Data |
| WISER:UN 1224 |
| WGK Germany:2 |
| hexane-2,3-dione |
| Chemidplus:0003848246 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:MO3140000 for cas# 3848-24-6 |
References:
Other Information:
Potential Blenders and core components note
| For Odor |
| No odor group found for these |
butter starter distillates FL/FR |
| acidic |
| acidic |
iso butyric acid FL/FR |
cyclohexyl acetic acid FL/FR |
2- methyl butyric acid FL/FR |
2- methyl-2-pentenoic acid FL/FR |
| aldehydic |
acetyl nonyryl FL/FR |
| balsamic |
2- acetyl furan FL/FR |
cinnamyl benzoate FL/FR |
| bready |
coffee furanone FL/FR |
| buttery |
acetoin FL/FR |
acetoin dimer FL/FR |
acetoin propylene glycol acetal FL/FR |
acetyl isobutyryl FL/FR |
acetyl propionyl FL/FR |
apple butter fragrance FR |
butter fragrance FR |
butter oil CO2 extract FL/FR |
butyl butyryl lactate FL/FR |
iso butyl lactate FL/FR |
butyl octanoate FL/FR |
2,3- heptane dione FL/FR |
3,4- hexane dione FL/FR |
| caramellic |
2-oxo butyric acid FL/FR |
caramel pentadione FL/FR |
cyclotene FL/FR |
cyclotene hydrate FL/FR |
alpha,alpha- dimethyl anisyl acetone FL/FR |
ethyl 2-hydroxy-2-methyl butyrate FL/FR |
ethyl cyclopentenolone FL/FR |
ethyl maltol FL/FR |
5- ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one FL/FR |
fenugreek absolute FL/FR |
geranyl crotonate FR |
immortelle absolute FL/FR |
levulinic acid FL/FR |
maltol FL/FR |
maltyl propionate FL/FR |
maple furanone FL/FR |
menthone lactone FL/FR |
mesitene lactone FR |
5- methyl furfural FL/FR |
rosefuran FL/FR |
shoyu furanone FL/FR |
strawberry furanone FL/FR |
strawberry furanone acetate FL/FR |
toffee furanone FL/FR |
| cheesy |
butyric acid FL/FR |
2- methyl valeric acid FL/FR |
| cocoa |
cocoa butter fragrance FR |
| coconut |
coconut decanone methyl FR |
coconut naphthalenone FL/FR |
delta- decalactone FL/FR |
delta-2- dodecenolactone FL/FR |
gamma- heptalactone FL/FR |
delta- nonalactone FL/FR |
gamma- nonalactone (aldehyde C-18 (so-called)) FL/FR |
gamma- octalactone FL/FR |
delta- undecalactone FL/FR |
| corn chip |
popcorn pyrimidine FL/FR |
| coumarinic |
epsilon- decalactone FL/FR |
tonka bean resinoid FR |
| creamy |
2,3- butane diol FR |
gamma- butyrolactone FL/FR |
creamy lactone FL/FR |
cyclotene propionate FL/FR |
3- heptyl dihydro-5-methyl-2(3H)-furanone FL/FR |
(Z)-gamma- jasmolactone FR |
delta- tridecalactone FL/FR |
para- vanillic acid FL/FR |
para- vanillyl alcohol FL/FR |
waxy lactone FL/FR |
| earthy |
1- nonen-3-ol FL/FR |
| ethereal |
ethyl 4-pentenoate FL/FR |
ethyl pyruvate FL/FR |
iso valeraldehyde propylene glycol acetal FL/FR |
| fatty |
butter esters FL/FR |
butyl undecylenate FL/FR |
(Z)- dairy lactone FL/FR |
7- decen-4-olide FL/FR |
ethyl undecylenate FL/FR |
delta- juniper lactone FL/FR |
4- methyl octanoic acid FL/FR |
| fermented |
butyl laevo-lactate FL/FR |
ethyl (E)-2-crotonate FL/FR |
| floral |
para- anisyl butyrate FL/FR |
benzyl lactate FL/FR |
jasmin absolute italy (from concrete) FL/FR |
jasmin absolute replacer FR |
jasmin pyranone FL/FR |
linalyl butyrate FL/FR |
para- methyl acetophenone FL/FR |
| fruity |
acetoin acetate FL/FR |
1- acetoxyacetone FL/FR |
bitter almond oil FL/FR |
iso amyl 2-methyl butyrate FL/FR |
amyl isobutyrate FL/FR |
(S)-delta- decalactone FL/FR |
gamma- decalactone FL/FR |
ethyl lactate FL/FR |
(E)- ethyl tiglate FL/FR |
farnesyl acetone FL/FR |
maltyl acetate FL/FR |
methyl (Z)-5-octenoate FL/FR |
2- methyl butyl butyrate FL/FR |
neryl propionate FL/FR |
2- nonanone FL/FR |
octyl butyrate FL/FR |
prenyl isobutyrate FL/FR |
sorbyl butyrate FL/FR |
strawberry furanone butyrate FL/FR |
tetrahydrofurfuryl acetate FL/FR |
gamma- undecalactone (aldehyde C-14 (so-called)) FL/FR |
2- undecanone FL/FR |
| green |
iso amyl 3-(2-furan) propionate FL/FR |
iso butyl benzyl carbinol FL/FR |
butyl lactate FL/FR |
(Z)-4- hepten-1-ol FL/FR |
(Z)-4- heptenal FL/FR |
(Z)-4- heptenal diethyl acetal FL/FR |
(Z)-3- hexen-1-yl butyrate FL/FR |
(E,Z)-2,6- nonadienal FL/FR |
| herbal |
butyl levulinate FL/FR |
| marine |
marine pyridine FR |
| mushroom |
3- octen-2-ol FL/FR |
1- octen-3-yl butyrate FL/FR |
| musty |
3- acetyl-2,5-dimethyl furan FL/FR |
| nutty |
2- acetyl-3-methyl pyrazine FL/FR |
2- acetyl-3,5(or 6)-dimethyl pyrazine FL/FR |
2,3- dimethyl pyrazine FL/FR |
2- ethyl pyrazine FL/FR |
filbert heptenone FL/FR |
(-)-(E,R)- filbertone FL/FR |
5- methyl quinoxaline FL/FR |
nutty cyclohexenone FL/FR |
| oily |
butter acids FL/FR |
| phenolic |
4- methyl-2,6-dimethoxyphenol FL/FR |
| plastic |
1- phenyl-1,2-propane dione FL/FR |
| soapy |
ethyl undecanoate FL/FR |
| spicy |
(E)- tiglic acid FL/FR |
| sweet |
vanilla oleoresin bali FL/FR |
| tonka |
6- amyl-alpha-pyrone FL/FR |
mint lactone FL/FR |
tonka bean absolute FR |
whiskey lactone FL/FR |
| tropical |
delta- dodecalactone FL/FR |
glyceryl 5-hydroxydecanoate FL/FR |
glyceryl 5-hydroxydodecanoate FL/FR |
| vanilla |
ortho- dimethyl hydroquinone FL/FR |
ethyl vanillin FL/FR |
ethyl vanillin isobutyrate FL/FR |
ethyl vanillin propylene glycol acetal FL/FR |
vanillin FL/FR |
vanillyl acetate FL/FR |
vanillyl isobutyrate FL/FR |
vanillylidene acetone FL/FR |
| vegetable |
methional FL/FR |
tetrahydrofurfuryl alcohol FL/FR |
| waxy |
allyl nonanoate FL/FR |
iso amyl decanoate FL/FR |
5(6)- decenoic acid FL/FR |
ethyl palmitate FL/FR |
2- methyl heptanoic acid FL/FR |
methyl laurate FL/FR |
2- nonanol FL/FR |
(E)-2- octen-1-yl butyrate FL/FR |
octyl 2-methyl butyrate FL/FR |
octyl isobutyrate FL/FR |
phenethyl octanoate FL/FR |
delta- tetradecalactone FL/FR |
undecanoic acid FL/FR |
| For Flavor |
| No flavor group found for these |
1- acetoxyacetone FL/FR |
2- acetyl-3,4,5,6-tetrahydropyridine FL |
allyl 2-furoate FL |
allyl methyl trisulfide FL |
amyl isobutyrate FL/FR |
benzyl disulfide FL |
benzyl lactate FL/FR |
butter nut rum flavor FL |
butyl octanoate FL/FR |
cinnamyl benzoate FL/FR |
coconut naphthalenone FL/FR |
cyclotene propionate FL/FR |
(S)-delta- decalactone FL/FR |
7- decen-4-olide FL/FR |
6- decenoic acid FL |
2,5- diethyl tetrahydrofuran FL |
alpha,alpha- dimethyl anisyl acetone FL/FR |
ortho- dimethyl hydroquinone FL/FR |
delta-2- dodecenolactone FL/FR |
ethyl 2-hydroxy-2-methyl butyrate FL/FR |
ethyl 4-pentenoate FL/FR |
ethyl butyryl lactate FL |
5- ethyl-2,3,4,5-tetramethyl-2-cyclohexen-1-one FL/FR |
farnesyl acetone FL/FR |
furfuryl acetone FL |
menthone lactone FL/FR |
3-( methyl thio) hexanal FL |
4,5- octane dione FL |
(E)-2- octen-1-yl butyrate FL/FR |
prenyl isobutyrate FL/FR |
rosefuran FL/FR |
sodium 4-methyl-2-oxovalerate FL |
|
iso amyl 3-(2-furan) propionate FL/FR |
| acidic |
| acidic |
iso butyric acid FL/FR |
levulinic acid FL/FR |
| aldehydic |
acetyl nonyryl FL/FR |
| alliaceous |
3- tetrahydrothiophenone FL |
| amber |
iso butyl benzyl carbinol FL/FR |
| anisic |
para- anisyl butyrate FL/FR |
| balsamic |
vanillylidene acetone FL/FR |
| berry |
maltyl acetate FL/FR |
| bitter |
glyceryl tributyrate FL |
| bready |
mango furanone FL |
| brown |
2-oxo butyric acid FL/FR |
5- methyl furfural FL/FR |
tetrahydrofurfuryl acetate FL/FR |
(E)- tiglic acid FL/FR |
| burnt |
furfuryl alcohol FL |
2- methyl quinoxaline FL |
| buttery |
acetoin propylene glycol acetal FL/FR |
bovolide FL |
butter cream frosting flavor FL |
butter enhancers FL |
creamy butter flavor FL |
sweet butter flavor FL |
butter flavor FL |
butter maple flavor FL |
butter nut vanilla flavor FL |
butter oil CO2 extract FL/FR |
butter pecan flavor FL |
butter praline flavor FL |
butter starter distillates FL/FR |
butter toffee flavor FL |
butter vanilla nut flavor FL |
iso butyl lactate FL/FR |
butyl laevo-lactate FL/FR |
butyroin FL |
diacetyl FL |
ghee flavor FL |
2,3- heptane dione FL/FR |
3,4- hexane dione FL/FR |
2- methyl valeric acid FL/FR |
(E)-2- pentenoic acid FL |
| cabbage |
methyl 2-thiofuroate FL |
| caramellic |
butter rum toffee flavor FL |
caramel dione FL |
caramel furanone FL |
caramel pentadione FL/FR |
cyclotene FL/FR |
cyclotene hydrate FL/FR |
ethyl maltol FL/FR |
5- ethyl-3,4,5,6-tetramethyl cyclohexen-2-one FL |
fenugreek absolute FL/FR |
maltol FL/FR |
maltyl propionate FL/FR |
maple furanone FL/FR |
3- methyl butyl 2-furyl butyrate FL |
1- phenyl-1,2-propane dione FL/FR |
shoyu furanone FL/FR |
strawberry furanone FL/FR |
strawberry furanone acetate FL/FR |
toffee furanone FL/FR |
| cheesy |
2- nonanone FL/FR |
| chocolate |
chocolate butter cream flavor FL |
| citrus |
butter lemon orange flavor FL |
| coconut |
delta- decalactone FL/FR |
(R)- massoia lactone FL |
6- methyl coumarin FL |
gamma- nonalactone (aldehyde C-18 (so-called)) FL/FR |
| coffee |
coffee distillates FL |
2- thiophene thiol FL |
| corn chip |
popcorn pyrimidine FL/FR |
| creamy |
acetoin FL/FR |
acetoin butyrate FL |
acetyl ethyl carbinol FL |
acetyl isobutyryl FL/FR |
6- amyl-alpha-pyrone FL/FR |
butter esters FL/FR |
butter fat enzyme modified with added butyric acid FL |
butyl butyryl lactate FL/FR |
creamy lactone FL/FR |
5(6)- decenoic acid FL/FR |
5,5- dibutyl dihydrofuran-2(3H)-one FL |
divanillin FL |
delta- dodecalactone FL/FR |
glyceryl 5-hydroxydecanoate FL/FR |
glyceryl 5-hydroxydodecanoate FL/FR |
jasmin pyranone FL/FR |
para- methyl acetophenone FL/FR |
mint lactone FL/FR |
delta- nonalactone FL/FR |
octyl isobutyrate FL/FR |
delta- tridecalactone FL/FR |
delta- undecalactone FL/FR |
gamma- undecalactone (aldehyde C-14 (so-called)) FL/FR |
para- vanillic acid FL/FR |
para- vanillyl alcohol FL/FR |
waxy lactone FL/FR |
| dairy |
acetoin dimer FL/FR |
methyl (Z)-5-octenoate FL/FR |
| earthy |
1- nonen-3-ol FL/FR |
| fatty |
butter acids FL/FR |
(Z)- dairy lactone FL/FR |
diacetyl trimer FL |
ethyl undecylenate FL/FR |
delta- juniper lactone FL/FR |
4- methyl octanoic acid FL/FR |
2,4- octadien-1-ol FL |
2,4- undecadienal FL |
(E,E)-2,4- undecadienal FL |
| floral |
jasmin absolute italy (from concrete) FL/FR |
linalyl butyrate FL/FR |
| fruity |
acetoin acetate FL/FR |
acetyl isovaleryl FL |
bitter almond oil FL/FR |
iso amyl 2-methyl butyrate FL/FR |
gamma- decalactone FL/FR |
ethyl lactate FL/FR |
(E)- ethyl tiglate FL/FR |
furfuryl valerate FL |
3- heptyl dihydro-5-methyl-2(3H)-furanone FL/FR |
2- methyl butyl butyrate FL/FR |
2- methyl butyric acid FL/FR |
2- pentanoyl furan FL |
phenethyl octanoate FL/FR |
sorbyl butyrate FL/FR |
strawberry furanone butyrate FL/FR |
iso valeraldehyde propylene glycol acetal FL/FR |
| green |
butyl lactate FL/FR |
heptanal 2,3-butane diol acetal FL |
(Z)-4- hepten-1-ol FL/FR |
(Z)-4- heptenal FL/FR |
(Z)-4- heptenal diethyl acetal FL/FR |
(Z)-3- hexen-1-yl butyrate FL/FR |
immortelle absolute FL/FR |
neryl propionate FL/FR |
(E,Z)-2,6- nonadienal FL/FR |
2,3- octane dione FL |
| herbal |
butyl levulinate FL/FR |
5- hydroxymethyl furfural FL |
| jammy |
ethyl cyclopentenolone FL/FR |
| lactonic |
gamma- heptalactone FL/FR |
gamma- octalactone FL/FR |
| metallic |
2,5- dihydroxy-1,4-dithiane FL |
| milky |
gamma- butyrolactone FL/FR |
| mushroom |
3- octen-2-ol FL/FR |
1- octen-3-yl butyrate FL/FR |
| musty |
ethyl (E)-2-crotonate FL/FR |
| nutty |
2- acetyl furan FL/FR |
3- acetyl-2,5-dimethyl furan FL/FR |
2- acetyl-3-methyl pyrazine FL/FR |
2- acetyl-3,5(or 6)-dimethyl pyrazine FL/FR |
butter pecan cake flavor FL |
coffee furanone FL/FR |
2,5- diethyl-3-methyl pyrazine FL |
2,3- dimethyl pyrazine FL/FR |
2- ethyl pyrazine FL/FR |
filbert heptenone FL/FR |
(-)-(E,R)- filbertone FL/FR |
5- methyl quinoxaline FL/FR |
nutty cyclohexenone FL/FR |
peanut oxazole FL |
tetrahydrofurfuryl alcohol FL/FR |
| phenolic |
4- methyl-2,6-dimethoxyphenol FL/FR |
| powdery |
powdery ketone FL |
| rummy |
ethyl pyruvate FL/FR |
| sour |
butyric acid FL/FR |
2- methyl-2-pentenoic acid FL/FR |
| spicy |
benzylidene acetone FL |
spiced butter rum flavor FL |
cinnamon butter pecan flavor FL |
cinnamon nut butter rum flavor FL |
| sweet |
cyclohexyl acetic acid FL/FR |
honey distillates FL |
vanilla butter nut flavor FL |
vanilla oleoresin bali FL/FR |
| toasted |
acetyl propionyl FL/FR |
| tomato |
methional FL/FR |
| vanilla |
ethyl vanillin FL/FR |
ethyl vanillin isobutyrate FL/FR |
ethyl vanillin propylene glycol acetal FL/FR |
vanillin FL/FR |
vanillyl acetate FL/FR |
vanillyl isobutyrate FL/FR |
| waxy |
allyl nonanoate FL/FR |
iso amyl decanoate FL/FR |
butyl undecylenate FL/FR |
epsilon- decalactone FL/FR |
ethyl palmitate FL/FR |
ethyl undecanoate FL/FR |
furfuryl octanoate FL |
2- methyl heptanoic acid FL/FR |
methyl laurate FL/FR |
2- nonanol FL/FR |
octyl 2-furoate FL |
octyl 2-methyl butyrate FL/FR |
octyl butyrate FL/FR |
delta- tetradecalactone FL/FR |
undecanoic acid FL/FR |
2- undecanone FL/FR |
| winey |
5- ethyl-2-methyl pyridine FL |
| woody |
whiskey lactone FL/FR |
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acetyl butyryl | | | acetyl butyryl natural | | | acetyl-N-butyryl | | | acetylbutyryl | | | butyryl acetyl | | 2,3- | hexane dione | | | hexane-2,3-dione | | 2,3- | hexanedione | | | methyl propyl diketone |
Articles:
| US Patents:3,952,024 - Furfurylthioacetone |
| PubMed:NTP Research Report on Respiratory Tract Toxicity of the Flavoring Agent 2,3-Hexanedione in Mice Exposed by Inhalation: Research Report 10 |
| US Patents:Certain 2,5-dimethyl-3-thiopyrazines |
| PubMed:Pheromone Chemistry of the Citrus Borer, Diploschema rotundicolle (Coleoptera: Cerambycidae) |
| PubMed:Chemical Reactivity and Respiratory Toxicity of the �-Diketone Flavoring Agents: 2,3-Butanedione, 2,3-Pentanedione, and 2,3-Hexanedione |
| PubMed:Exposures and Emissions in Coffee Roasting Facilities and Caf�s: Diacetyl, 2,3-Pentanedione, and Other Volatile Organic Compounds |
| PubMed:Models of toxicity of diacetyl and alternative diones |
| PubMed:Increased sensitivity of OSHA method analysis of diacetyl and 2,3-pentanedione in air |
| PubMed:Enantioselective Synthesis of Vicinal (R,R)-Diols by Saccharomyces cerevisiae Butanediol Dehydrogenase |
| PubMed:The Male-Produced Aggregation-Sex Pheromone of the Cerambycid Beetle Plagionotus detritus ssp. detritus |
| PubMed:Evaluation of the hypersensitivity potential of alternative butter flavorings |
| PubMed:Probing mechanisms of axonopathy. Part II: Protein targets of 2,5-hexanedione, the neurotoxic metabolite of the aliphatic solvent n-hexane |
| PubMed:The Role of Minor Pheromone Components in Segregating 14 Species of Longhorned Beetles (Coleoptera: Cerambycidae) of the Subfamily Cerambycinae |
| PubMed:Identification and measurement of diacetyl substitutes in dry bakery mix production |
| PubMed:Synthesis, characterization, powder X-ray diffraction analysis, thermal stability, antioxidant properties and enzyme inhibitions of M(II)-Schiff base ligand complexes |
| PubMed:Apoptotic and necrotic effects of hexanedione derivatives on the human neuroblastoma line SK-N-SH |
| PubMed:Potent inhibition of human carbonyl reductase 1 (CBR1) by the prenylated chalconoid xanthohumol and its related prenylflavonoids isoxanthohumol and 8-prenylnaringenin |
| PubMed:Formaldehyde, glyoxal, urethane, methyl carbamate, 2,3-butanedione, 2,3-hexanedione, ethyl acrylate, dibromoacetonitrile and 2-hydroxypropionitrile induce chromosome loss in Saccharomyces cerevis |
| PubMed:Physiological and oral parameters contribute prediction of retronasal aroma release in an elderly cohort |
| PubMed:Occupational exposures of flour dust and airborne chemicals at bakeries in Taiwan |
| PubMed:Design, synthesis and biological evaluation of benzo[e][1,2,4]triazin-7(1H)-one and [1,2,4]-triazino[5,6,1-jk]carbazol-6-one derivatives as dual inhibitors of beta-amyloid aggregation and acetyl/ |
| PubMed:Inhibition of the reconstituted mitochondrial oxoglutarate carrier by arginine-specific reagents |
| PubMed:A comparison of the apoptotic and cytotoxic effects of hexanedione derivatives on human non-neuronal lines and the neuroblastoma line SH-SY5Y |
| PubMed:A multi-technique analytical approach for impurity profiling during synthesis: The case of difluprednate |
| PubMed:Evaluation of four �-diketones for toll-like receptor-4 (TLR-4) activation in a human transfected cell line |
| PubMed:Characterization of a newly isolated strain Comamonas sp. ZF-3 involved in typical organics degradation in coking wastewater |
| PubMed:(R)-3-hydroxyhexan-2-one is a major pheromone component of Anelaphus inflaticollis (Coleoptera: Cerambycidae) |
| PubMed:Application of gas-diffusion microextraction to solid samples using the chromatographic determination of �-diketones in bread as a case study |
| PubMed:Carbonyl reductases from Daphnia are regulated by redox cycling compounds |
| PubMed:Sampling and Analytical Method for Alpha-Dicarbonyl Flavoring Compounds via Derivatization with o-Phenylenediamine and Analysis Using GC-NPD |
| PubMed:S-nitrosoglutathione covalently modifies cysteine residues of human carbonyl reductase 1 and affects its activity |
| PubMed:Airway injury in an in vitro human epithelium-fibroblast model of diacetyl vapor exposure: diacetyl-induced basal/suprabasal spongiosis |
| PubMed:Purification, characterization, and gene cloning of glycerol dehydrogenase from Hansenula ofunaensis, and its expression for production of optically active diol |
| PubMed:Molecular mechanism of hexane neuropathy: significant differences in pharmacokinetics between 2.3-, 2.4-, and 2.5-hexanedione |
| PubMed:Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members |
| PubMed:Stereoselective oxidation of aliphatic diols and reduction of hydroxy-ketones with galactitol dehydrogenase from Rhodobacter sphaeroides D |
| PubMed:Adiponectin enhances the responsiveness of the olfactory system |
| PubMed:Rapid and sensitive determination of the intermediates of advanced glycation end products in the human nail by ultra-performance liquid chromatography with electrospray ionization time-of-flight |
| PubMed:Male-produced aggregation pheromone of the cerambycid beetle Neoclytus acuminatus acuminatus |
| PubMed:Synthesis and antimicrobial activity of 3-hydroxyimino-5-methyl-2-hexanone(HIMH) and its dioxime derivative |
| PubMed:Antimicrobial effect of Cu(II) complexes containing oxime ligands |
| PubMed:Multi-capillary column-ion mobility spectrometry of volatile metabolites emitted by Saccharomyces cerevisiae |
| PubMed:Key aroma compounds and metabolic profiling of Debaryomyces hansenii L1-1-fermented Flos Sophorae |
| PubMed:The kinetic method as a structural diagnostic tool: ionized alpha-diketones as loosely one-electron bonded diacylium ion dimers |
| PubMed:Mass, IR, electronic and EPR spectral studies on transition metal complexes with a new tetradentate 12-membered new macrocyclic ligand |
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