|
Category:food-contact surface of paper and paperboard
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.08300 @ 25.00 °C.
|
| Boiling Point: | -19.50 °C. @ 760.00 mm Hg (est)
|
| Vapor Pressure: | 3463.820068 mmHg @ 25.00 °C. (est) |
| Flash Point: | 133.00 °F. TCC ( 56.11 °C. )
|
| logP (o/w): | 0.350 |
| Soluble in: |
| | water, 400000 mg/L @ 20 °C (exp) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intravenous-cat LDLo 30 mg/kg BLOOD: OTHER CHANGES Acta Pharmacologica et Toxicologica. Vol. 8, Pg. 275, 1952.
intravenous-dog LDLo 70 mg/kg International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
parenteral-frog LDLo 800 ug/kg International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
oral-guinea pig LD50 260 mg/kg Journal of Industrial Hygiene and Toxicology. Vol. 23, Pg. 259, 1941.
unreported-man LDLo 477 mg/kg "Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.
oral-man TDLo 643 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITING
LUNGS, THORAX, OR RESPIRATION: RESPIRATORY OBSTRUCTION
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH Japanese Journal of Toxicology. Vol. 4, Pg. 261, 1991.
oral-man TDLo 646 mg/kg GASTROINTESTINAL: NAUSEA OR VOMITING
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
GASTROINTESTINAL: GASTRITIS Japanese Journal of Toxicology. Vol. 4, Pg. 261, 1991.
oral-mouse LD50 42 mg/kg BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: EXCITEMENT
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD National Technical Information Service. Vol. AD-A125-539
intraperitoneal-mouse LDLo 16 mg/kg Toxicology and Applied Pharmacology. Vol. 23, Pg. 288, 1972.
intravenous-rabbit LDLo 48 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 213, 1955.
intravenous-rat LD50 87 mg/kg Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 221, Pg. 166, 1954.
oral-rat LD50 100 mg/kg Food and Chemical Toxicology. Vol. 26, Pg. 447, 1988.
|
| Dermal Toxicity: |
subcutaneous-dog LDLo 350 mg/kg International Polymer Science and Technology. Vol. 3, Pg. 93, 1976.
subcutaneous-mouse LD50 300 mg/kg LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
skin-rabbit LD50 270 uL/kg Union Carbide Data Sheet. Vol. 4/21/1967
subcutaneous-rabbit LDLo 240 mg/kg JAMA, Journal of the American Medical Association. Vol. 62, Pg. 984, 1914.
subcutaneous-rat LD50 420 mg/kg LUNGS, THORAX, OR RESPIRATION: BRONCHIOLAR CONSTRICTION
LUNGS, THORAX, OR RESPIRATION: ACUTE PULMONARY EDEMA Acta Pharmacologica et Toxicologica. Vol. 6, Pg. 299, 1950.
|
| Inhalation Toxicity: |
inhalation-cat LCLo 400 mg/m3/2H "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 69, 1982.
inhalation-human TCLo 17 mg/m3/30M SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES JAMA, Journal of the American Medical Association. Vol. 165, Pg. 1908, 1957.
inhalation-man TCLo 300 ug/m3 BEHAVIORAL: AGGRESSION
SENSE ORGANS AND SPECIAL SENSES: OTHER CHANGES: OLFACTION Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 12(7), Pg. 20, 1968.
inhalation-mouse LC50 454000 mg/m3/4H Current Toxicology. Vol. 1, Pg. 47, 1993.
inhalation-rat LC50 203 mg/m3 BEHAVIORAL: EXCITEMENT
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
PERIPHERAL NERVE AND SENSATION: SPASTIC PARALYSIS WITH OR WITHOUT SENSORY CHANGE Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 18(2), Pg. 55, 1974.
|
Safety in Use Information:
| Category: | | food-contact surface of paper and paperboard |
| Recommendation for formaldehyde usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for formaldehyde flavor usage levels up to: |
| | not for flavor use.
|
| NOEL (No Observed Effect Level): | 15 (mg/kg bw per day) |
Safety References:
European Food Safety Authority (EFSA) reference(s):
|
Flavouring Group Evaluation 8 (FGE.08)[1]: Aliphatic and alicyclic mono-, di-, tri-, and polysulphides with or without additional oxygenated functional groups from chemical group 20 View page or View pdf
|
Scientific Opinion on Flavouring Group Evaluation 20, Revision 3(FGE.20Rev3): Benzyl alcohols, benzaldehydes, a related acetal, benzoic acids, and related esters from chemical groups 23 and 30 View page or View pdf
|
Report of ESCO WG on non-plastic Food Contact Materials View page or View pdf
|
Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to use of formaldehyde as a preservative during the manufacture and preparation of food additives View page or View pdf
|
Reasoned opinion on the modification of the existing MRLs for metaldehyde in certain legume vegetables and pulses View page or View pdf
|
Scientific Opinion on the re-evaluation of hexamethylene tetramine (E 239) as a food additive View page or View pdf
|
Scientific Opinion on the safety and efficacy of formaldehyde as a feed hygiene substance in feed for pigs and poultry View page or View pdf
|
EFSA scientific advice to EC on accumulating formaldehyde in GM soybeans View page or View pdf
|
| EPI System: View |
| EPA-Iris:IRIS |
| ClinicalTrials.gov:search |
| Daily Med:search |
| NIOSH International Chemical Safety Cards:search |
| NIOSH Pocket Guide:search |
| Chemical Carcinogenesis Research Information System:Search |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| Carcinogenic Potency Database:Search |
| EPA GENetic TOXicology:Search |
| EPA Substance Registry Services (TSCA):50-00-0 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :712 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| formaldehyde |
| Chemidplus:0000050000 |
| EPA/NOAA CAMEO:hazardous materials |
| RTECS:50-00-0 |
References:
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| FDA Substances Added to Food (formerly EAFUS): | View |
| FDA Indirect Additives used in Food Contact Substances: | View |
| CHEBI: | View |
| CHEMBL: | View |
| Metabolomics Database: | Search |
| UM BBD: | Search |
| KEGG (GenomeNet): | C00067 |
| HMDB (The Human Metabolome Database): | HMDB01426 |
| FooDB: | FDB009445 |
| YMDB (Yeast Metabolome Database): | YMDB00321 |
| Export Tariff Code: | 2912.11.0000 |
| FDA Listing of Food Additive Status: | View |
| VCF-Online: | VCF Volatile Compounds in Food |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations: •pure formaldehyde is not avail commercially because of its tendency to polymerize. it is sold as aqueous solutions containing from 37% to 50% formaldehyde by wt & varying amounts of methanol.
•marketed under the trade name formcel, soln in methanol, n-butanol, and isobutanol. ...
•aq formaldehyde, known as formalin, is usually 37% by weight of formaldehyde, though more concn soln are available. formalin is the general-purpose formaldehyde of commerce supplied unstabilized or methanol-stabilized. formaldehyde may also exist in the form of the cyclic trimer trioxane. this is a fairly stable cmpd that does not easily release formaldehyde. ...
•grade: aqueous solutions: 37%, 44%, 50% inhibited (with varying percentages of methanol) or stabilized or unstabilized (methanol-free), also available in solution in n-butanol, ethanol, or urea; usp (37% aqueous solution containing methanol).
•soluble concentrate; hot fogging concentrate
•formaldehyde is available in the united states as as paraformaldehyde. paraformaldehyde is available as a powdered or flaked product that contains the equivalent of 90-93% formaldehyde, a maximum of 9% water, and a maximum of 0.03% acidity as formic acid. it is readily soluble in hot water with the evolution of formaldehyde vapors ...
•formalin consists of an aqueous solution of formaldehyde, usually containing about 37% formaldehyde and 12-15% methanol. formalin
|
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | formalin | | | formic aldehyde | | | formol | | | methaldehyde | | | methanal | | | methyl aldehyde | | | paraform |
Articles:
|
a highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. in solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (from reynolds, martindale the extra pharmacopoeia, 30th ed, p717) A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons.
|