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Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | White to light yellow crystals or powder (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 242.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 449.30 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 463.00 °F. TCC ( 239.70 °C. ) (est)
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| logP (o/w): | 0.670 |
| Soluble in: |
| | water, 1.506e+004 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 78 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
VASCULAR: REGIONAL OR GENERAL ARTERIOLAR OR VENOUS DILATION
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 151, Pg. 719, 1957.
oral-rat LDLo 250 mg/kg
National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. Vol. 5, Pg. 28, 1953.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic agents |
| Recommendation for ninhydrin usage levels up to: | | | not for fragrance use.
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| Recommendation for ninhydrin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2,2- | dihydroxy-1,3-indandione | | 2,2- | dihydroxy-1,3-indanedione | | 2,2- | dihydroxy-1H-indene-1,3(2H)-dione | | 2,2- | dihydroxy-2-hydrocyclopenta[1,2-a]benzene-1,3-dione | | 2,2- | dihydroxy-2H-indene-1,3-dione | | 2,2- | dihydroxyindane-1,3-dione | | 2,2- | dihydroxyindene-1,3-dione | | | indan-1,2,3-trione | | 1,3- | indandione, 2,2-dihydroxy- | | 1,2,3- | indantrione | | 1H- | indene-1,3(2H)-dione, 2,2-dihydroxy- | | | ninhydrine |
Articles:
| PubMed:Tetrahydroindeno[1',2':4,5]pyrrolo[1,2-a]imidazol-5(1H)-ones as Novel Neonicotinoid Insecticides: Reaction Selectivity and Substituent Effects on the Activity Level. |
| PubMed:Purification and identification of novel antioxidant peptides from egg white protein and their antioxidant activities. |
| PubMed:Isolation and identification of cyclic lipopeptides from Paenibacillus ehimensis, strain IB-X-b. |
| PubMed:Actinophytocola sediminis sp. nov., an actinomycete isolated from a marine sediment. |
| PubMed:Validation and application of an improved method for the rapid determination of proline in grape berries. |
| PubMed:Proteolytic activities of kiwifruit actinidin (Actinidia deliciosa cv. Hayward) on different fibrous and globular proteins: a comparative study of actinidin with papain. |
| PubMed:Determining the effects of routine fingermark detection techniques on the subsequent recovery and analysis of explosive residues on various substrates. |
| PubMed:Quantification of taurine in energy drinks using ¹H NMR. |
| PubMed:An investigation into the enhancement of fingermarks in blood on fruit and vegetables. |
| PubMed:One- and two-dimensional high-performance thin-layer chromatography as an alternative analytical tool for investigating polyphenol-protein interactions. |
| PubMed:A modified ninhydrin micro-assay for determination of total cyanogens in plants. |
| PubMed:Preparation, characterization and antioxidant property of water-soluble ferulic acid grafted chitosan. |
| PubMed:Characterization and application of a L-specific amino acid oxidase from Rhodococcus sp. AIU LAB-3. |
| PubMed:Direct separation and detection of biogenic amines by ion-pair liquid chromatography with chemiluminescent nitrogen detector. |
| PubMed:Separation of gamma-aminobutyric acid from fermented broth. |
| PubMed:Accelerated hydrolysis method to estimate the amino acid content of wheat (Triticum durum Desf.) flour using microwave irradiation. |
| PubMed:Analysis of Monosodium l-Glutamate in Food Products by High-Performance Thin Layer Chromatography. |
| PubMed:[Humidity as a necessary condition for latent fingerprint detection with ninhydrin--a practice-oriented and inexpensive method using potassium citrate]. |
| PubMed:Melamine and Cyanuric Acid do not interfere with Bradford and Ninhydrin assays for protein determination. |
| PubMed:Wheat gluten amino acid composition analysis by high-performance anion-exchange chromatography with integrated pulsed amperometric detection. |
| PubMed:Various methods for determination of the degree of N-acetylation of chitin and chitosan: a review. |
| PubMed:An antibacterial pyrazole derivative from Burkholderia glumae, a bacterial pathogen of rice. |
| PubMed:Characterization of antimicrobial properties on the growth of S. aureus of novel renewable blends of gliadins and chitosan of interest in food packaging and coating applications. |
| PubMed:Impurity profile of amino acids? |
| PubMed:A review of the current literature on aetiology and measurement methods of halitosis. |
| PubMed:Effect of the electrical currents generated by the intestinal smooth muscle layers on pancreatic enzyme activity: an in vitro study. |
| PubMed:Rapid analysis of taurine in energy drinks using amino acid analyzer and Fourier transform infrared (FTIR) spectroscopy as basis for toxicological evaluation. |
| PubMed:Determination of trace hydroxyl radicals by flow injection spectrofluorometry and its analytical application. |
| PubMed:Simultaneous determination of riboflavin, pyridoxine, nicotinamide, caffeine and taurine in energy drinks by planar chromatography-multiple detection with confirmation by electrospray ionization mass spectrometry. |
| PubMed:Specificity of a Vibrio vulnificus aminopeptidase toward kinins and other peptidyl substrates. |
| PubMed:A modified ninhydrin reagent using ascorbic acid instead of potassium cyanide. |
| PubMed:Model studies on the influence of high hydrostatic pressure on the formation of glycated arginine modifications at elevated temperatures. |
| PubMed:Dietary S-methylmethionine, a component of foods, has choline-sparing activity in chickens. |
| PubMed:Influence of starter culture ratios and warm room treatment on free fatty acid and amino acid in Swiss cheese. |
| PubMed:Chromogenic derivatives of AHTN (6-acetyl-1,1,2,4,4,7-hexamethyltetralin) react with amino acids and protein in vitro. Spectral characteristics of the colour products. |
| PubMed:Applications of the ninhydrin reaction for analysis of amino acids, peptides, and proteins to agricultural and biomedical sciences. |
| PubMed:Characterization and comparison of commercially available German and American cockroach allergen extracts. |
| PubMed:Effect of exogenous histidine and Garcinia cambogia on histamine formation in skipjack (Katsuwonus pelamis) homogenates. |
| PubMed:Proteolysis in Manchego-type cheese salted by brine vacuum impregnation. |
| PubMed:Diversity of the polar lipids of the food-borne pathogen Listeria monocytogenes. |
| PubMed:A comparison of methods for determining total body protein. |
| PubMed:Metabolic activities of pseudomonads in batch cultures in extract of minced lamb. |
| PubMed:Flow injection spectrophotometric determination of aspartame in dietary products. |
| PubMed:Tumour-promoting activity of ninhydrin on mouse skin. |
| PubMed:Heat treatment of infant formula: effect on postprandial serum alpha-amino-nitrogen concentrations in very-low-birth-weight infants. |
| PubMed:Identification of alpha-carboxamidated and carboxy-terminal glycine forms of peptides in bovine hypothalamus, bovine pituitary and porcine heart extracts. |
| PubMed:Detection and identification of the cross-linking amino acids N tau- and N pi-(2'-amino-2'-carboxy-ethyl)-L-histidine ("histidinoalanine", HAL) in heated milk products. |
| PubMed:Monitoring tripeptidase activity using capillary electrophoresis. Comparison with the ninhydrin assay. |
| PubMed:High sugar content of extracts interferes with colorimetric determination of amino acids and free proline. |
| PubMed:Quantitative analysis of protein deposits on hydrophilic soft contact lenses: I. Comparison to visual methods of analysis. II. Deposit variation among FDA lens material groups. |
| PubMed:A potent thromboxane formation inhibitor in green tea leaves. |
| PubMed:Determination of taurine in infant formulas using ultrafiltration and cation-exchange chromatography. |
| PubMed:A procedure for total protein determination with special application to allergenic extract standardization. |
| PubMed:Some chemical properties of maitotoxin, a putative calcium channel agonist isolated from a marine dinoflagellate. |
| PubMed:Identification of ninhydrin-positive caprolactam metabolites in the rat. |
| PubMed:Studies on LHRH and physiological fluid amino acids in human colostrum and milk. |
| PubMed:Isolation and liquid chromatographic determination of the cyclic peptide mycotoxin cyclosporin A from rice. |
| PubMed:Determination of biogenic amines in cheese and some other food products by high-performance liquid chromatography in combination with thermo-sensitized reaction detection. |
| PubMed:First evidence for the occurrence of N delta-acetyl-L-ornithine and quantification of the free amino acids in the cultivated mushroom, Pleurotus ostreatus. |
| PubMed:Investigations on the origin of two radiation-induced compounds in irradiated meat. |
| PubMed:Diet and medications giving positive ninhydrin reactions on TLC in a newborn urinary screening program. |
| PubMed:Evaluation of lysinoalanine determinations in food proteins. |
| PubMed:Comparison of thin-layer chromatographic detection methods for histamine from food extracts. |
| PubMed:Design assembly of an inexpensive, automated microbore amino acid analyzer: separation and quantitation of amino acids in physiological fluids. |
| PubMed:[Influence of various thermal processes and microwaves on the amino acid composition of food products: implications on their nutritional value]. |
| PubMed:A screening method for protein characterization and differentiation. |
| PubMed:Rapid determination of tryptophan in beans (Phaseolus vulgaris) by the acid ninhydrin method. |
| PubMed:Direct estimation of lysine in corn meals by the ninhydrin color reaction. |
| PubMed:Characterization of growth stimulants in corn steep for lactic streptococci. |
| PubMed:Growth of lactic acid bacteria in waste waters of vegetable-processing plants. |
| PubMed:EVALUATION OF THE EXTRACT-RELEASE VOLUME PHENOMENON AS A RAPID TEST FOR DETECTING SPOILAGE IN BEEF. |
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2,2-dihydroxy-1h-indene-1,3-(2h)-dione. reagent toxic to skin and mucus membranes. it is used in chemical assay for peptide bonds, i.e., protein determinations and has radiosensitizing properties.
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3D/inchi