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Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 437.60 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 0.000000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 425.00 °F. TCC ( 218.40 °C. ) (est)
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| logP (o/w): | 6.231 (est) |
| Soluble in: |
| | water, 0.07195 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic agents |
| Recommendation for linoleamide usage levels up to: | | | not for fragrance use.
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| Recommendation for linoleamide flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
| | antistatic agents |
| | opacifying agents |
| | viscosity controlling agents |
Occurrence (nature, food, other): note
Synonyms:
| | linoleic acid amide | | (9Z,12Z)- | octadeca-9,12-dien-1-amide | | (9Z,12Z)- | octadeca-9,12-dienamide | | (9Z,12Z)- | octadeca-9,12-dienoic acid amide | | (Z,Z)-9,12- | octadecadienamide | | 9,12- | octadecadienamide, (9Z,12Z)- |
Articles:
| PubMed:[Potential cytostatic effect of the maleimide derivative 1-(4-Cl-benzyl)-3-Cl-4-(CF3-phenylamino)-1-H-pyrrol-2,5-dione]. |
| PubMed:The macamide N-3-methoxybenzyl-linoleamide is a time-dependent fatty acid amide hydrolase (FAAH) inhibitor. |
| PubMed:Primary fatty acid amide metabolism: conversion of fatty acids and an ethanolamine in N18TG2 and SCP cells. |
| PubMed:Anti-inflammatory effects of fatty acids isolated from Chromolaena odorata. |
| PubMed:Hypolipidemic and antioxidant activity of the novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor KY-455 in rabbits and hamsters. |
| PubMed:The biohydrogenation of linoleamide in vitro and its effects on linoleic acid concentration in duodenal contents of sheep. |
| PubMed:Effect of oleamide on Ca(2+) signaling in human bladder cancer cells. |
| PubMed:Linoleamide, a brain lipid that induces sleep, increases cytosolic Ca2+ levels in MDCK renal tubular cells. |
| PubMed:[Effect of presynaptic dopaminergic agonism on the immobility of mice in the forced swimming test]. |
| PubMed:Mass spectrometric identification of N-phenyllinoleamide metabolites in mouse peritoneal macrophages. |
| PubMed:Effects of NB-598, a potent squalene epoxidase inhibitor, on the apical membrane uptake of cholesterol and basolateral membrane secretion of lipids in Caco-2 cells. |
| PubMed:[Effect of some GABA, glycine, or glutamic acid derivatives on the forced swimming test in mice]. |
| PubMed:[Are there glutamatergic, anti-GABAergic or antiglycinergic components in the action mechanism of adamantamines? Study of convulsions induced by amantadine or 1-adamantylcyclopentanamine in mice]. |
| PubMed:[Effect of glutamic acid palmitamide or linoleamide on convulsions induced by pentetrazole]. |
| PubMed:[Oral dyskinesia in rats after a single administration of haloperidol combined with GABA-linoleamide. A model of dyskinesia in man]. |
| PubMed:Cholesterol-lowering effect of N-(alpha-methylbenzyl)linoleamide (melinamide) in cholesterol-fed diabetic rats. |
| PubMed:Determination of oxidation products of N-phenyllinoleamide: Spanish toxic oil syndrome studies. |
| PubMed:[Effect of glycine-steatamide or glutamic acid palmitamide on oral dyskinesia, obtained by a single administration of haloperidol combined with GABA-linoleamide in rats]. |
| PubMed:[Synthesis and pharmacological study of glutamic acid palmitamide and linoleamide]. |
| PubMed:Chain-shortening of a xenobiotic acyl compound by the peroxisomal beta-oxidation system in rat liver. |
| PubMed:Mechanism of the inhibition of cholesterol absorption by DL-melinamide: inhibition of cholesterol esterification. |
| PubMed:[Vacuous chewing after haloperidol and GABA-linoleamide administration in the rat]. |
| PubMed:[Effect of GABA-linoleamide and glycine-linoleamide on catalepsy in the rat after chronic administration of reserpine]. |
| PubMed:Inhibitory effect of melinamide on cholesterol solubility in mixed micellar solution of sodium taurocholate. |
| PubMed:[Effects of GABA-ergic and glycinergic agents on pentamethylenetetrazole-induced convulsions in rats submitted to repeated injections of reserpine]. |
| PubMed:[Effect of GABA-linoleamide and glycine linoleamide on pentamethylenetetrazole convulsions]. |
| PubMed:[Effect of glycine linoleamide on haloperidol and reserpine catalepsy in the rat]. |
| PubMed:[Effect of glycine linoleamide on thermoregulation in mice and rats]. |
| PubMed:[Synthesis and pharmacological study of glycine linoleamide]. |
| PubMed:[The effect of various new GABAergics on motor and oral stereotypes with apomorphine in the rat]. |
| PubMed:[2 new GABA-ergics (GABA-linoleamide and GABA-steatamide). On 2 experimental models of depression]. |
| PubMed:[Effect of GABA linoleamide on thermoregulation in mice exposed to low temperatures]. |
| PubMed:[Action of GABA-linoleamide on blood cholesterol in rats]. |
| PubMed:[Effect of GABA linoleamide on internal temperature regulation in the mouse]. |
| PubMed:[Psychopharmacologic profile of a new product: GABA linoleamide (Gabalid)]. |
| PubMed:14C-labelling of a hypocholesterolemic agents, N-(alpha-methylbenzyl) linoleamide. |
| PubMed:Linoleic acid amides: effect on cholesteremia and atherosclerosis. |
| PubMed:Metabolism of linoleamides. II. Absorption, distribution, excretion and metabolism of N-[alpha-phenyl-beta-(p-tolyl)ethyl]linoleamide. |
| PubMed:Metabolism of linoleamides. I. Absorption, excretion and metabolism of N-(alpha-methylbenzyl)linoleamide in rat and man. |
| PubMed:Effect of (-)N-[alpha-phenyl-beta-(p-tolyl)ethyl] linoleamide on lipid levels in serum and liver in cholesterol-fed rats. |
| PubMed:Inhibition of cholesterol absorption by (-)N-[alpha-phenyl-beta-(p-tolyl)ethyl] linoleamide in rats. |
| PubMed:Influence of N( -methylbenzyl)linoleamide upon cholesterol metabolism in rats. |
| PubMed:Enzymatic hydrolysis of N-(alpha-methylbenzyl)linoleamide. |
| PubMed:Cholesterol esterification in vitro with DL-N-(alpha-methylbenzyl)-(1-14C)linoleamide. |
| PubMed:The effect of (--)N-(alpha-phenyl-beta-(p-tolyl)ethyl) linoleamide on experimental atherosclerosis in rabbits. |
| PubMed:The effect of N-(alpha-methylbenzyl) linoleamide on cholesterol metabolism in rats. |
| PubMed:Cholesterol-lowering effects of DL-N-(alpha-methylbenzyl)-linoleamide and its optically active isomers in cholesterol-fed animals. |
| PubMed:The effect of N-(alpha-methylbenzyl) linoleamide on experimental atherosclerosis in rabbits. |
| PubMed:Agents affecting lipid metabolism. XXXVI. Effect of N-cyclohexyl linoleamide on hepatic cholesterogenesis in vitro. |
| PubMed:Influence of N-cyclohexyl linoleamide on cholesterol synthesis by rat liver slices. |
| PubMed:Effect of N-cyclohexyl linoleamide on cholesterol metabolism in rats. |
| PubMed:Linolexamide (N-cyclohexyl linoleamide) in experimental atherosclerosis in rabbits. |
| PubMed:The effect of N-cyclohexyl linoleamide on experimental atherosclerosis in rabbits. |
| PubMed:N-cyclohexyl linoleamide: metabolism and cholesterol-lowering effect in rats. |
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