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Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 222.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 586.30 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 492.00 °F. TCC ( 255.40 °C. ) (est)
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| logP (o/w): | 2.220 (est) |
| Soluble in: |
| | water, 566.3 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Quassin
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| Carbosynth |
| For experimental / research use only. |
| Quassin
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| Coompo |
| For experimental / research use only. |
| Quassin from Plants ≥96%
Odor: characteristic Use: Quassin has been identified to be the antilarval principle present in this plant and was effective against mosquito larvae at a concentration of 6 ppm. Quassin was over five times as active as carbaryl, a synthetic antilarval agent.
Quassin inhibits the steroidogenesis in Rat Leydig Cells In vitro. |
Safety Information:
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | cosmetic agents |
| Recommendation for quassin usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for quassin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2,12- | dimethoxypicrasa-2,12-diene-1,11,16-trione | | (3aS,6aR,7aS,8S,11aS,11bS,11cS)-1,3a,4,5,6a,7,7a,8,11,11a,11b,11c- | dodecahydro-2,10-dimethoxy-3,8,11a,11c-tetramethyl dibenzo(de,g)chromene-1,5,11-trione | | | nigakilactone D | | 3ab,6ab,7,7aa,8,11a,11ba,11c- | octahydro-2,10-dimethoxy-3,8a,11ab,11cb-tetramethylphenanthro[10,1-bc]pyran-1,5,11(4H)-trione | | | picrasa-2,12-diene-1,11,16-trione, 2,12-dimethoxy- | | | picrasmin | | | quassine |
Articles:
| PubMed:Antiulcerogenic effects and possible mechanism of action of Quassia amara (L. Simaroubaceae) extract and its bioactive principles in rats. |
| PubMed:Liquid chromatography electrospray ionization tandem mass spectrometric determination of quassin and neoquassin in fruits and vegetables. |
| PubMed:Reproductive activities of female albino rats treated with quassin, a bioactive triterpenoid from stem bark extract of Quassia amara. |
| PubMed:Quassinoid constituents of Quassia amara L. leaf herbal tea. Impact on its antimalarial activity and cytotoxicity. |
| PubMed:[Examination of original plant of Jamaica quassia extract, a natural bittering agent, based on composition of the constituents]. |
| PubMed:[Analysis of constituents in Jamaica quassia extract, a natural bittering agent]. |
| PubMed:Quassinoids from Picrasma crenata. |
| PubMed:Indonesian medicinal plants. XVII. Characterization of quassinoids from the stems of Quassia indica. |
| PubMed:Liquid chromatography electrospray ionization tandem mass spectrometric determination of quassin and neoquassin in fruits and vegetables. |
| PubMed:Reproductive activities of female albino rats treated with quassin, a bioactive triterpenoid from stem bark extract of Quassia amara. |
| PubMed:[Examination of original plant of Jamaica quassia extract, a natural bittering agent, based on composition of the constituents]. |
| PubMed:Quassin alters the immunological patterns of murine macrophages through generation of nitric oxide to exert antileishmanial activity. |
| PubMed:Inhibition of CYP1A1 by Quassinoids found in Picrasma excelsa. |
| PubMed:[Analysis of constituents in Jamaica quassia extract, a natural bittering agent]. |
| PubMed:Quassinoids from Picrasma crenata. |
| PubMed:Antiviral activity of simalikalactone D, a quassinoid from Quassia africana. |
| PubMed:Total synthesis of (+)-quassin. |
| PubMed:[Weitz' aminium salt initiated electron transfer reactions and application to the synthesis of natural products]. |
| PubMed:Indonesian medicinal plants. XVII. Characterization of quassinoids from the stems of Quassia indica. |
| PubMed:Antifertility activity of Quassia amara: quassin inhibits the steroidogenesis in rat Leydig cells in vitro. |
| PubMed:2-Methoxycanthin-6-one: A New Alkaloid from the Stem Wood of Quassia amara. |
| PubMed:A microwell cytotoxicity assay using Artemia salina (brine shrimp). |
| PubMed:Effect of quassin on the metabolism of catecholamines in different life cycle stages of Culex quinquefasciatus. |
| PubMed:Larvicidal efficacy of Quassin against Culex quinquefasciatus. |
| PubMed:Activity of quassinoids as antifeedants against aphids. |
| PubMed:Use of microdilution to assess in vitro antiamoebic activities of Brucea javanica fruits, Simarouba amara stem, and a number of quassinoids. |
| PubMed:1H- and 13C-NMR spectroscopic studies of selected quassinoids. |
| PubMed:Acute insecticidal activity of quassin and its congeners against the American cockroach. |
| PubMed:Production of the triterpenoid quassin in callus and cell suspension cultures of Picrasma quassioides Bennett. |
| PubMed:Quassinoid bitter principles. II. |
| PubMed:Antifeedant activity of quassinoids. |
| PubMed:An enzyme-linked immunosorbent assay for quassin and closely related metabolites. |
| PubMed:Structure-activity relationships for binding and inactivation of rabbit reticulocyte ribosomes by quassinoid antineoplastic agents. |
| PubMed:[Antiamebic properties of some derivatives of ailantone and quassin]. |
| PubMed:A thin-layer chromatographic method for the determination of "quassin" in cosmetic preparations. |
| PubMed:[Research on the constituents of the bark of the subspontaneous Ailanthus glandulosa Desf. of Liguria. I. Identification of two amaroids (quassin and neopuassin)]. |
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3D/inchi
